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Updated: Apr 2, 2026
Investigation into Deep Breathing through Measurement of Ventilatory Parameters and Observation of Breathing Patterns
Published on: September 16, 2019
Effect of manual diaphragmatic release on ventilatory function and quality of life in women with rheumatoid
Saher Lotfy Elgayar1, Mohamed Bayoumi Ibrahim Bayoumi1,2
1Department of Physiotherapy, Faculty of Allied Medical Sciences, Middle East University, Amman, Jordan.
Introduction:
Rheumatoid arthritis (RA) could lead to several respiratory dysfunctions, impairing quality of life.
Objective:
To evaluate the effect of manual diaphragmatic release (MDR) added to aerobic training (AT) on ventilatory function, diaphragmatic motion, aerobic capacity, and quality of life, compared with AT alone, in women with RA.
Methods:
Eighty women with RA were equally assigned to either the MDR group, which received MDR and AT, or the control group, which received AT only, for 8 weeks. Outcomes included forced vital capacity (FVC) and total lung capacity (TLC), diaphragmatic motion, maximal oxygen consumption (Vo2max), and the Rheumatoid Arthritis Quality of Life Questionnaire (RA QoL).
Results:
Analysis was conducted using ANCOVA. Relative to the controls, the MDR group showed significantly greater post-study FVC (mean difference (MD) = 3.99%; 95% CI: 1.14 to 6.83; p = 0.007), TLC (MD = 3.75%; 95% CI: 1.10 to 6.41; p = 0.006), diaphragmatic motion (MD = 7.5 mm; 95% CI: 1.11 to 9.89; p = 0.001), and Vo2max (MD = 5.02 ml/kg/min; 95% CI: 1.19 to 8.4; p = 0.01), along with a significantly lower RA QoL score (MD = -3.64; 95% CI: -5.39 to -1.9; p = 0.001).
Conclusion:
In women with RA, adding MDR to AT was more effective than AT alone in improving ventilatory function, diaphragmatic motion, aerobic capacity, and quality of life.
Trial Registration:
ClinicalTrials.gov, prospective, NCT06716008.
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