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Updated: Apr 2, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Temporal change in patients with mitral annular calcification after successful aortic valve intervention
Owais Abdul-Kafi1, Maroun Chedid1, Tremayne Ansani1
1Valve Science Center, Minneapolis Heart Institute foundation, Minneapolis, MN, USA; Minneapolis Heart Institute, Abbott Northwestern Hospital, MN, USA.
Background:
Patients with severe aortic valve stenosis and concomitant mild to moderate mitral stenosis (MS) or mitral regurgitation (MR) from mitral annular calcification (MAC) often undergo aortic valve replacement (AVR) while sparing the mitral valve. This study aimed to analyze the rate of progression of mitral valve disease in patients with MAC undergoing AVR.
Methods:
A retrospective cohort study was conducted on 147 patients with MS and/or MR and MAC undergoing AVR at Allina Health in 2012-2022. The rate of progression for MR, MS, left ventricular ejection fraction (LVEF), and survival probability were assessed at a median follow-up of 2.0 (1.24-3.70) years.
Results:
The mean age was 78 ± 10 years. Most patients were female (66%) with NYHA class III symptoms (70%) prior to AVR, and the majority underwent TAVR (93%). Most patients had MS ranging from trace to moderate range (90%) and MR ranging from trace to moderate range (91%) prior to the procedure. There was no significant change in MS or MR severity, or mortality (p = 0.47) based on MAC severity within the follow up duration.
Conclusion:
Overall, patients with MAC with moderate or less MS and/or MR and aortic stenosis had no significant change in MS or MR severity and no need for mitral valve intervention during 6 years of follow-up after AVR.
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