Related Experiment Video
Updated: Jul 9, 2026

12:55
Strategies for Tracking Anastasis, A Cell Survival Phenomenon that Reverses Apoptosis
Published on: February 16, 2015
18.8K
Whi3key old fashioned: a condensate cocktail for cell fate decisions
Cameron O Schmitz1, Ankur Jain1
1Whitehead Institute for Biomedical Research, 455 Main Street, Cambridge, MA 02142, USA; Department of Biology, Massachusetts Institute of Technology, 31 Ames Street, Cambridge, MA 02139, USA.
Trends in Cell Biology
|March 31, 2026
Abstract:
How do single cells weigh conflicting internal and external signals to arrive at unambiguous fate decisions? Peskett et al. reveal that a partnership between two condensates, Whi3 assemblies and P-bodies, forms a decision module in budding yeast that encodes aging information and enables context-dependent choices between proliferation, senescence, and mating.

