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Aescin and rutin mitigate hyperthyroidism-induced multisystem dysfunction via antioxidant and anti-inflammatory

Minnatullah A Makadi1, Ibrahim A Ibrahim2, Hoda I Bahr2

  • 1Department of Biochemistry and Molecular Biology, Faculty of Veterinary Medicine, Arish University, Al Arish, North Sinai, 45511, Egypt.

Scientific Reports
|March 31, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
AescinCardioprotectionHepatoprotectionHyperthyroidismNeuroprotectionOxidative stressRutin

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Hyperthyroidism II: Pathophysiology01:27

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Hyperthyroidism is a hypermetabolic state caused by elevated levels of thyroid hormones, triiodothyronine (T3) and thyroxine (T4). It results from dysregulation at the thyroid, pituitary, or immune system level and affects multiple organ systems.PathophysiologyThe most common cause of hyperthyroidism is Graves’ disease, an autoimmune disorder in which antibodies, specifically thyroid-stimulating antibodies (TSAb), a subtype of TSH receptor antibodies (TRAb), bind to and activate TSH receptors...

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