Related Experiment Video

Updated: Apr 2, 2026

Author Spotlight: Advancing the Use of Tissue Chip Technology for Studying Human Tissues
09:10

Author Spotlight: Advancing the Use of Tissue Chip Technology for Studying Human Tissues

Published on: January 12, 2024

3.9K

Nanoscopic analysis of tight junction organization in in vitro blood-brain barrier models

Ayk Waldow1, Andreas Brachner2, Nicolas Perriere3

  • 1Clinical Physiology/Nutritional Medicine, Department of Gastroenterology, Rheumatology and Infectious Diseases, Charité - Universitätsmedizin Berlin, 1 Hindenburgdamm 30, 12203, Berlin, Germany.

Fluids and Barriers of the CNS
|April 1, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Blood brain barrierClaudinEndotheliaEpitheliaIn vitro modelsNanoscopySTEDTight junction

More Related Videos

A Triple Culture Cell System Modeling the Human Blood-Brain Barrier
09:21

A Triple Culture Cell System Modeling the Human Blood-Brain Barrier

Published on: November 30, 2021

4.7K
An In Vitro Model of the Blood-brain Barrier Using Impedance Spectroscopy: A Focus on T Cell-endothelial Cell Interaction
10:17

An In Vitro Model of the Blood-brain Barrier Using Impedance Spectroscopy: A Focus on T Cell-endothelial Cell Interaction

Published on: December 8, 2016

11.9K

Related Experiment Videos

Last Updated: Apr 2, 2026

Author Spotlight: Advancing the Use of Tissue Chip Technology for Studying Human Tissues
09:10

Author Spotlight: Advancing the Use of Tissue Chip Technology for Studying Human Tissues

Published on: January 12, 2024

3.9K
A Triple Culture Cell System Modeling the Human Blood-Brain Barrier
09:21

A Triple Culture Cell System Modeling the Human Blood-Brain Barrier

Published on: November 30, 2021

4.7K
An In Vitro Model of the Blood-brain Barrier Using Impedance Spectroscopy: A Focus on T Cell-endothelial Cell Interaction
10:17

An In Vitro Model of the Blood-brain Barrier Using Impedance Spectroscopy: A Focus on T Cell-endothelial Cell Interaction

Published on: December 8, 2016

11.9K

Related Concept Videos

The Blood-brain Barrier00:49

The Blood-brain Barrier

55.4K
Overview
55.4K
Tight Junctions01:29

Tight Junctions

8.9K
Tight junctions are molecular seals between cells that prevent the leaking of fluids, ions, and other small solutes across cavities and compartments in multicellular organisms. They are mainly composed of claudin and occludin transmembrane proteins, and other proteins such as tricellulin and JAM (junctional adhesion molecule). All these proteins are 4-pass transmembrane proteins, except JAM, which is a single-pass transmembrane protein belonging to the immunoglobulin superfamily. The...
8.9K

Articles linked to this work by shared authors, journal, and citation graph.

Educational and training needs of regulatory professionals for non-animal methodologies: Insights from a survey.

ALTEX·2026

The Current Status of the 3Rs Principles in Animal Use in Bosnia and Herzegovina: Overview and Future Perspectives.

Animals : an open access journal from MDPI·2026

Finding a place for new approach methodologies (NAMs) in biomedical research.

Lab animal·2026

Establishment and Optimization of a Human Flow-Based Hollow Fiber In Vitro Blood-Brain Barrier Model for Systemic Inflammatory Responses.

Pharmaceutics·2026

New approach methodologies for next-generation risk assessment of nanomaterials and nano-enabled products.

Nano convergence·2026

A homoeriodictyol sodium mouthwash reduces bitterness sensitivity in patients with gynecological cancer receiving carboplatin-based chemotherapy.

Scientific reports·2026

TNFα-induced endothelial extracellular vesicles regulate astrocyte function: an integrated transcriptomic and proteomic study.

Fluids and barriers of the CNS·2026

No evidence of major integrative brain clearance impairment in an Alzheimer´s disease model of transgenic APPswe/PS1dE9 mice.

Fluids and barriers of the CNS·2026

Pulsatile intraspinal pressure drives post-traumatic syringomyelia: evidence supporting the CSF pulsatile pressure dynamic equilibrium hypothesis.

Fluids and barriers of the CNS·2026

Brain parenchyma deformation and strain in patients with spontaneous intracranial hypotension.

Fluids and barriers of the CNS·2026

Neonatal blood biomarkers related to development of hydrocephalus.

Fluids and barriers of the CNS·2026

Blood-brain barrier water permeability is elevated in type 2 diabetes and obesity: associations with cognitive function and metabolic markers.

Fluids and barriers of the CNS·2026

Targeting the nervous system: Mechanistic insights into neuro-tumor communication and therapeutic opportunities.

Acta pharmaceutica Sinica. B·2026

Intercellular Mitochondrial Transfer in the Nervous System: Roles of Tunneling Nanotubes, Mitochondrial Extracellular Vesicles, and Neuroimmune Bioenergetic Interactions.

Molecular neurobiology·2026

Wiring the developing brain: The Rho GTPase signaling network in neurodevelopmental disorders.

Neurobiology of disease·2026

Discovery of H-10 as a potent and safe GABAA receptor positive allosteric modulator: A novel benzothiazine-triazole lead compound with broad-spectrum anticonvulsant activity.

European journal of medicinal chemistry·2026

Long-term stability and reproducibility of frozen plasma control samples for hepatitis B virus, hepatitis C virus, and human immunodeficiency virus by quantitative PCR: Implications for retrospective testing in hemovigilance.

Transfusion·2026

Early treatment prevents neuronal loss in experimental status epilepticus: A magnetic resonance spectroscopic imaging study.

Epilepsia·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us