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Related Concept Videos

Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

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Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
466

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Related Experiment Video

Updated: Apr 2, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
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Transseptal Device Comparison for Improved Puncture and Streamlined Mitral Edge-To-Edge Repair.

Anastasia E I Malek1, Meghali Singhal1, Wes Soliman1

  • 1Santa Barbara Cottage Hospital, Santa Barbara, California.

Journal of the Society for Cardiovascular Angiography & Interventions
|April 1, 2026
PubMed
Summary
This summary is machine-generated.

The VersaCross Large Access system (VLA) significantly reduces transseptal puncture (TSP) and catheter delivery times for mitral valve repair. This technique enhances procedural efficiency and predictability in the catheterization laboratory.

Keywords:
MitraClipVersaCrosstranscatheter repairtransseptal puncture

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Area of Science:

  • Cardiovascular Interventions
  • Structural Heart Disease
  • Medical Device Technology

Background:

  • Transseptal puncture (TSP) complexity is influenced by septal anatomy, impacting left atrial access for mitral valve repair.
  • Comparing needle-based TSP techniques is crucial for optimizing large mitral transcatheter edge-to-edge repair procedures.

Purpose of the Study:

  • To compare the efficacy of the VersaCross Large Access system (VLA) against mechanical needle (MN) and radiofrequency-powered needle (RFN) techniques for transseptal puncture.
  • To evaluate the impact of different TSP techniques on procedural time and efficiency during transcatheter mitral valve repair.

Main Methods:

  • Retrospective review of consecutive MitraClip procedures utilizing MN (n=28), RFN (n=55), and VLA (n=109).
  • Evaluation of TSP success, time to TSP, steerable guide catheter (SGC) delivery, clip deployment, and overall procedure time.
  • Assessment of acute adverse events associated with each transseptal technique.

Main Results:

  • All TSP procedures were successful with no adverse events.
  • VLA demonstrated the shortest TSP time (15.8 min) and time to SGC delivery (5.4 min) compared to MN and RFN.
  • VLA resulted in the lowest overall procedure time (96 min) and more consistent TSP and SGC delivery times.

Conclusions:

  • The VersaCross Large Access system (VLA) significantly shortens transseptal puncture times and improves steerable guide catheter delivery efficiency.
  • Adopting VLA can enhance overall procedure time, leading to greater predictability and efficiency in the catheterization laboratory.
  • Transseptal technique selection is a key factor in optimizing outcomes for transcatheter mitral valve repair procedures.