Related Experiment Video
Updated: Apr 2, 2026

Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance
Published on: December 28, 2017
Interconnected worlds: a comprehensive review of fungal defenses, antimicrobial resistance, and their evolutionary
Yuan Sui1, Mir Muhammad Nizamani2, Entaj Tarafder2
1Chongqing Key Laboratory for Germplasm Innovation of Special Aromatic Spice Plants, College of Smart Agriculture/Institute of Special Plants, Chongqing University of Arts and Sciences, Yongchuan, Chongqing 402160, China Centre of Advanced Study, University of Calcutta Kolkata India https://ror.org/01e7v7w47.
Abstract:
Fungal defense mechanisms and antimicrobial resistance to therapeutic remedies represent a complex and evolving challenge. This review explores the multifaceted processes that determine fungal resistance and covers cellular, evolutionary, and global aspects. Key factors, such as cell wall integrity, efflux pumps, and adaptive responses, are examined, along with interdisciplinary analytical techniques used to elucidate defense mechanisms. Evolutionary drivers, including natural selection and horizontal gene transfer, are also discussed. The review emphasizes the importance of global coordination, personalized medicine, ethical principles, and sustainable practices in both healthcare and agriculture to address the growing problem of antimicrobial resistance to therapeutic drugs. It synthesizes existing literature and offers recommendations for future research and initiatives designed to support a global effort capable of proactively addressing antimicrobial resistance and overcoming fungal defense mechanisms, thereby mitigating their impact on human health and food production.
More Related Videos
Related Concept Videos
Antifungal Agents
Defense Against Bacterial Pathogens
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
Development of Antibiotic Resistance
Overview of Fungi
Defenses Against Pathogens and Herbivores
Fungal Group Zygomycota

