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Global insights into pediatric ischemic stroke: a bibliometric and visualization analysis

Yangyang Zhou1, Xiaoye Huang2, Kai Cai2

  • 1Department of Neurosurgery, Shenzhen Children's Hospital, Shenzhen, China.

Frontiers in Medicine
|April 1, 2026
PubMed

Insights

Research on pediatric ischemic stroke (IS) shows a rising trend, with key hotspots in causes, treatments, and collaboration. Enhanced global partnerships are crucial for advancing pediatric IS research and care.

Area of Science:

  • Neurology
  • Pediatrics
  • Bibliometrics

Background:

  • Pediatric ischemic stroke (IS) is a serious condition impacting children's long-term health due to neurological issues.
  • Understanding research trends is vital for improving diagnosis and treatment of IS in children.

Purpose of the Study:

  • To conduct a comprehensive bibliometric analysis of pediatric IS research from 2000 to 2024.
  • To identify key research trends, influential publications, and collaboration patterns in pediatric IS.

Main Methods:

  • Publications on pediatric IS were gathered from Web of Science Core Collection and PubMed.
  • Bibliometric analysis and visualization were performed using VOSviewer, CiteSpace, and the Bibliometrix R package.

Main Results:

  • Publication trends for pediatric IS have steadily increased since 2000.
  • The United States leads in research output and collaboration; Hospital for Sick Children (Canada) is a leading institution.
  • Research focuses on etiology, clinical interventions, and multidisciplinary management of pediatric IS.

Conclusions:

  • Bibliometric analysis reveals evolving research landscape in pediatric IS.
  • Increased international and institutional collaboration is recommended to advance pediatric IS knowledge and resource sharing.
Abstract

Keywords:
bibliometric analysischildrenischemic strokemechanical thrombolysispediatric

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