Evaluation and management of premenstrual dysphoric disorder

Shea A Nagle1, Pamela J Murray1,2, Emily B Allen3,4

  • 1Division of Adolescent and Young Adult Medicine, Boston Children's Hospital.

Insights

Premenstrual dysphoric disorder (PMDD) diagnosis and treatment can be challenging, especially for diverse populations. This review offers pediatricians practical guidelines for evaluating and managing PMDD, considering recent research and emerging treatment options.

Area of Science:

  • Reproductive Psychiatry
  • Pediatric Gynecology
  • Mental Health

Background:

  • Premenstrual dysphoric disorder (PMDD) significantly impacts quality of life.
  • Diagnostic delays are common, hindering timely treatment initiation.
  • Challenges in care access and diagnosis are noted, particularly for marginalized groups.

Purpose of the Study:

  • To review current evidence for evaluating and treating PMDD.
  • To provide practical guidelines for pediatric providers.
  • To address special considerations for diverse patient populations.

Main Methods:

  • Literature review of recent research on PMDD evaluation and treatment.
  • Synthesis of evidence relevant to pediatric care.
  • Focus on pathophysiology, current treatments, and future management.

Main Results:

  • Difficulties in patient presentation, diagnosis, and treatment for PMDD are highlighted.
  • Comorbid mental health disorders and marginalized identities can exacerbate challenges.
  • Established treatments include SSRIs and oral contraceptive pills; new insights into pathophysiology and treatments are emerging.

Conclusions:

  • Provides practical guidelines for pediatricians on PMDD evaluation and management.
  • Emphasizes the need for special considerations for diverse populations.
  • Aims to improve care for pediatric patients with PMDD.
Abstract

Related Concept Videos

Depressive Disorders: MDD and Dysthymia01:27

Depressive Disorders: MDD and Dysthymia

Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
1.1K
Disorders of the Female Reproductive System01:24

Disorders of the Female Reproductive System

The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
4.8K
Mitral Valve Prolapse II: Assessment and Management01:22

Mitral Valve Prolapse II: Assessment and Management

IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...
1.1K
Antidepressant Drugs: MAOIs and Other Agents01:23

Antidepressant Drugs: MAOIs and Other Agents

Atypical antidepressants, including bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), and vilazodone (Viibryd), offer unique mechanisms of action. Bupropion weakly inhibits dopamine and norepinephrine reuptake, aiding depression treatment and smoking cessation, with a low risk of sexual dysfunction. Mirtazapine enhances serotonin and norepinephrine neurotransmission, leading to sedation, increased appetite, and weight gain. As a result, it helps treat...
1.2K
Dysrhythmias VII: Nursing Management of Dysrhythmias01:25

Dysrhythmias VII: Nursing Management of Dysrhythmias

Nursing management of dysrhythmias involves the following:AssessmentSubjective Assessment:The initial step involves gathering patient-reported symptoms such as dizziness, palpitations, and chest discomfort. It is crucial to collect a detailed history, including previous heart conditions, current medication use, and lifestyle factors like caffeine and alcohol consumption.Objective Assessment:This involves observing clinical signs such as jugular venous distention, cool and pale skin, and...
526
Mania and Antimanic Drugs: Overview01:24

Mania and Antimanic Drugs: Overview

Mania, a psychological condition characterized by elevated mood, increased energy, and reduced sleep need, is part of the bipolar disorder cycle. The exact cause of mania isn't entirely known, but it is thought to be a combination of genetic, environmental, and neurological factors. Bipolar disorder involves alternating manic and depressive episodes. Mood stabilizers like lithium, antipsychotics, and anticonvulsants help manage these episodes. Lithium carbonate is particularly effective as...
774