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Updated: May 23, 2026
03:55
Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
Published on: June 9, 2023
1.1K
Systemic Treatment of Thyroid Cancer: ASCO Guideline
Nabil F Saba1, Nofisat Ismaila2, Douglas Adkins3
1Emory University, Atlanta, GA.
Summary
This guideline provides evidence-based recommendations for systemic therapy in various thyroid cancers, including differentiated, anaplastic, and medullary types. It aims to improve treatment strategies and patient outcomes.
Area of Science:
- Oncology
- Clinical Guidelines
- Evidence-Based Medicine
Background:
- Thyroid cancer treatment requires tailored systemic therapy approaches.
- Current treatment strategies vary based on cancer subtype and stage.
- Systemic therapy plays a crucial role in managing advanced thyroid cancers.
Purpose of the Study:
- To develop evidence-based recommendations for systemic therapy in diverse thyroid cancer types.
- To guide clinicians in selecting appropriate systemic treatments for patients.
- To synthesize current evidence on the efficacy and safety of systemic therapies.
Main Methods:
- A multidisciplinary Expert Panel convened by the American Society of Clinical Oncology.
- Systematic literature review of studies published between 2000 and 2025.
- Inclusion of systematic reviews, meta-analyses, RCTs, and observational studies.
- Evaluation of outcomes including overall survival, disease-free survival, and safety.
Main Results:
- Sixty-six publications formed the evidence base for the guideline.
- Recommendations cover differentiated, poorly differentiated, anaplastic, and medullary thyroid cancers.
- The guideline synthesizes evidence on systemic therapy effectiveness.
Conclusions:
- Evidence-based recommendations are provided for systemic therapy in specific thyroid cancer subtypes.
- The guideline aims to optimize treatment decisions for thyroid cancer patients.
- Further details are available via the American Society of Clinical Oncology website.
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