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Mobile ECG for QTc assessment in cLQTS: A step toward remote monitoring
Nicole J van Steijn1, Auke T Bergeman2, Christian van der Werf1
1Heart Center, Department of Clinical Cardiology, Amsterdam UMC location University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands; Amsterdam Cardiovascular Sciences, Heart Failure and arrhythmias, Amsterdam UMC location University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands; Cardiology Centres of the Netherlands, Burgemeester Verderlaan 15, 3544 AD Utrecht, the Netherlands.
Introduction:
Handheld mobile ECG (mECG) devices offer potential for remote QTc surveillance in congenital long QT syndrome (cLQTS), but validation against standard 12‑lead ECGs is limited.
Methods And Results:
We studied 102 cLQTS patients (median age 36), using consecutive 12‑lead ECGs and KardiaMobile 1 L and 6 L recordings. Agreement with 12‑lead ECGs was assessed using Lin's concordance correlation coefficient (CCC) and Bland-Altman analysis. Mean biases were < 10 ms, within the predefined threshold for excellent agreement. Reproducibility was high.
Conclusion:
These findings support the cautious integration of mECG-based QTc monitoring for high-risk cLQTS patients.
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