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In-Hospital Outcomes of Robotic-Assisted Cholecystectomy in Obese versus Normal-Weight Patients: A National Inpatient
Palak Dutta1, Rohit Ganduboina2, Aman Sinha3
1Department of Surgery, University of Illinois Chicago, Chicago, Illinois.
The Journal of Surgical Research
|April 1, 2026
Summary
Robotic-assisted cholecystectomy (RC) is safe for obese patients, showing lower mortality and similar complication rates compared to normal-weight individuals. This minimally invasive approach may mitigate risks associated with obesity in gallbladder surgery.
Area of Science:
- Minimally Invasive Surgery
- Bariatric Surgery Outcomes
- Gastrointestinal Surgery
Background:
- Obesity is linked to increased risks and technical challenges in cholecystectomy.
- Robotic-assisted cholecystectomy (RC) offers potential advantages for managing obese patients.
Purpose of the Study:
- To compare in-hospital outcomes of RC between obese and normal-weight patients.
- To evaluate the safety and efficacy of RC in an obese population.
Main Methods:
- Retrospective analysis of National Inpatient Sample data (2016-2021).
- Inclusion of 15,048 adult patients undergoing RC, stratified into obese (BMI ≥30 kg/m²; n=4570) and normal-weight (BMI 18-25 kg/m²; n=10,478) groups.
- Analysis of demographics, comorbidities, hospital characteristics, and in-hospital outcomes using multivariable models.
Main Results:
- Obese patients (30% of cohort) were younger and had significantly lower in-hospital mortality (aOR 0.27) and infection rates (aOR 0.33).
- No significant differences were observed in other complication rates or rates of conversion to open surgery.
- RC appears safe and effective in selected obese individuals undergoing cholecystectomy.
Conclusions:
- Robotic-assisted cholecystectomy is increasingly utilized in obese patients and demonstrates safety in carefully selected individuals.
- Obese patients undergoing RC exhibit lower in-hospital mortality and comparable complication rates to normal-weight patients, despite higher comorbidity burdens.
- Further research is needed to address potential selection bias and evaluate long-term outcomes.

