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Updated: Apr 3, 2026

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
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Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions

Published on: November 30, 2022

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Design and synthesis of sorbicillinoid-derived bibenzyl and brominated analogues as anti-inflammatory agents

Bei Zhang1, Zhipeng Xu2, Meng Zhang1

  • 1Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy/State Key Laboratory of Bioactive Molecules and Druggability Assessment/International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Ministry of Education (MOE) of China, Jinan University, Guangzhou 510632, China.

Bioorganic & Medicinal Chemistry Letters
|April 1, 2026
PubMed

Keywords:
Anti-inflammatory effectsBibenzyl analoguesBrominated analoguesNLRP3NO productionSorbicillinoid

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