Related Experiment Video
Updated: Apr 3, 2026
07:08
Investigating Object Representations in the Macaque Dorsal Visual Stream Using Single-unit Recordings
Published on: August 1, 2018
8.8K
Dataset of cortical and subcortical single neuron activity during value-based tasks in macaque monkey
Liza London1, Marques Love1, Zachary R Zeisler1
1Nash Family Department of Neuroscience, Lipschultz Center for Cognitive Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Scientific Data
|April 1, 2026
Summary
This study details a large neural dataset from macaque monkeys performing value-based decision-making tasks. It provides insights into how frontal and subcortical brain regions interact to guide choices toward rewards in uncertain situations.
Area of Science:
- Cognitive Neuroscience
- Neurobiology
- Decision Science
Background:
- Understanding how the brain guides choices toward rewards in uncertain environments is a key challenge.
- Frontal cortex and subcortical structure interactions are crucial for decision-making.
- Distinct subregions of the frontal cortex and their unique contributions to decision-making remain unclear.
Purpose of the Study:
- To present an extensive dataset of neural recordings from macaque monkeys performing value-based decision-making tasks.
- To investigate the functional roles and interactions of frontal and subcortical brain regions in reward-guided decision-making.
- To reveal cross-areal dynamics of decision-making within the frontal cortex.
Main Methods:
- Recorded neural activity from 16,495 neurons across 22 anatomically verified areas in 2 macaque monkeys.
- Collected data over 340 behavioral sessions involving probabilistic value-based decision-making tasks.
- Utilized cytoarchitectural features of stained tissue for electrode localization and anatomical verification.
Main Results:
- The dataset includes detailed behavioral data, neuronal spike times, and precise electrode locations.
- Enables detailed analysis of neural activity during probabilistic reward-guided choices.
- Provides a foundation for understanding the complex interplay between distinct brain regions.
Conclusions:
- This comprehensive dataset facilitates further research into the functions of frontal and subcortical regions.
- It aids in resolving the neural mechanisms underlying reward-guided choice behavior.
- Offers a valuable resource for investigating inter-regional neural dynamics in decision-making.
