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Association study of the CSN2 gene with milk yield in the Sapera goat
Santiananda Arta Asmarasari1, Galih Ari Wirawan Siregar2, Ferdy Saputra1
1Research Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Cibinong Science Center, Bogor, Indonesia.
Objective:
This research was conducted to assess the influence of CSN2 exon 7 milk production and the additive and dominance effects.
Materials And Methods:
DNA was isolated from 64 goats that possessed the CSN2 gene and subjected to a polymerase chain reaction and genotyping by Sanger sequencing.Genotype effect can be assessed through analysis of variance and the generalized linear model, which can estimate additive and dominance effects.
Results:
Dairy traits are greatly influenced by the crucial role played by the CSN2 gene. The influence of SNP g.8946C > T on milk yield (MY) is statistically significant (p < 0.05). Nevertheless, the impact of SNP g.8956G > A on MY is not statistically significant. Furthermore, the MY of Sapera goats is affected by both Parity (p <0.01) and days in milk (p < 0.01).
Conclusion:
The CC genotype demonstrates a higher MY without noticeable additive or dominance effects. Evaluating the SNP g.8946C > T necessitates many samples and phenotypes.
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