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Updated: Apr 3, 2026

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Isolation of Leukocytes from the Murine Tissues at the Maternal-Fetal Interface
Published on: May 21, 2015
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Obstetrical Impact of Anti-MUT (Anti-MNS35) Alloimmunization
Mathilde Gavillet1,2, Tobias Gleich-Nagel1, Helene Legardeur3
1Interregional Blood Transfusion SRC Bern Ltd., Bern, Switzerland.
Summary
Maternal alloimmunization against the rare MUT antigen can cause severe hemolytic disease of the fetus and newborn (HDFN). Early identification and multidisciplinary management are crucial for successful pregnancy outcomes in cases of rare red blood cell alloimmunization.
Area of Science:
- Hematology
- Immunology
- Obstetrics
Background:
- Hemolytic disease of the fetus and newborn (HDFN) is a serious condition caused by maternal antibodies attacking fetal red blood cells (RBCs).
- While common antibodies like anti-D are well-known, antibodies against low-prevalence antigens (LPAs) are often underrecognized.
Keywords:
AlloimmunizationAnti-MUT antibodyGYPA*Hut (MNS35)Hemolytic disease of the fetus and newbornLow-prevalence antigenMore Related Videos
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