Prognostic Value of the Mannheim Peritonitis Index in Predicting Mortality Following Emergency Surgery for Hollow

Hong Quan Dang1, Van Bi Nguyen2, Quoc Viet Cao2

  • 1Department of Surgery, Faculty of Medicine, Can Tho University of Medicine and Pharmacy, Can Tho, Vietnam.

Abstract

Insights

The Mannheim peritonitis index (MPI) accurately predicts mortality in patients with secondary peritonitis. An MPI score of 25 or higher identifies high-risk individuals for better surgical decision-making.

Area of Science:

  • Surgical Gastroenterology
  • Critical Care Medicine
  • Epidemiology

Background:

  • Perforation peritonitis presents a significant global health challenge with high mortality rates.
  • Effective early risk stratification is crucial, especially in resource-limited healthcare environments.
  • The Mannheim peritonitis index (MPI) is a validated prognostic tool, yet its utility in Vietnamese populations requires further investigation.

Purpose of the Study:

  • To assess the prognostic accuracy of the Mannheim peritonitis index (MPI) in predicting in-hospital mortality.
  • To evaluate MPI's performance in patients undergoing surgery for secondary peritonitis caused by hollow viscus perforation in Vietnam.

Main Methods:

  • A prospective observational study was conducted with 176 patients in southern Vietnam.
  • Clinical data were collected to compute MPI scores, and outcomes were analyzed using ROC curves and logistic regression.

Main Results:

  • The study population had a mean age of 64.9 years, with 70.5% males. Generalized peritonitis was prevalent (96%).
  • Overall mortality was 21%. The MPI demonstrated strong predictive capability (AUC = 0.944).
  • An MPI score ≥25 showed high sensitivity (91.9%) and specificity (79.9%) for mortality prediction. Feculent peritonitis and preoperative organ failure were independent predictors.

Conclusions:

  • The Mannheim peritonitis index (MPI) is a reliable tool for early mortality risk stratification in secondary peritonitis.
  • Integrating an MPI threshold of ≥25 into clinical practice can aid in identifying high-risk patients for timely intervention.

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