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Updated: Apr 3, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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From alkynes to spiroindole δ-lactams via a copper-nitrenoid intermediate featuring unusual 1,1-addition and high

Zhiqiang Ren1, Tianhui Feng1, Yeyao Li1

  • 1Department of New Energy & New Functional Materials, Shaanxi Key Laboratory of Chemical Reaction Engineering, School of Chemistry and Chemical Engineerin Yan'an University Yan'an 716000 P. R. China renzhiqiang@yau.edu.cn yqzhang@yau.edu.cn.

Chemical Science
|April 2, 2026
PubMed

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