Case Report: Treatment of ultra-late phrenic nerve stimulation after cardiac resynchronization therapy with
Frontiers in Cardiovascular Medicine
|April 2, 2026
Abstract:
Ultra-late phrenic nerve stimulation (PNS) without evidence of lead dislodgement after cardiac resynchronization therapy (CRT) can be frequently solved by reprogramming and seldom leads to reintervention. We reported a case of super-response to CRT patient, PNS occurred after twelve years of the surgery. Reprogramming the parameters was ineffective. We innovatively used a double-layer spacer isolation technique to effectively isolate the left ventricular lead and the phrenic nerve, achieving the effect of cardiac resynchronization therapy.


