Post-Myocardial Infarction Ventricular Septal Defect Percutaneous Closure

Shikha Jha1, Parnian Soltani2, Abdelkader Almanfi3

  • 1University of Wisconsin Madison, Madison, Wisconsin, USA.

JACC. Case Reports
|April 2, 2026
PubMed

Insights

Transcatheter closure offers a viable alternative for treating post-myocardial infarction ventricular septal defects (PMIVSD) in high-risk patients. A novel venovenous loop approach provides a safe and effective minimally invasive option for PMIVSD closure.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Cardiac Surgery

Background:

  • Ventricular septal rupture (VSR) is a rare but severe complication following myocardial infarction (MI), associated with high mortality rates.
  • Current guidelines recommend immediate surgical closure for VSR, despite its risks.
Abstract