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AI Chatbots for Mental Health Self-Management: Lived Experience-Centered Qualitative Study.

Dong Whi Yoo1, Jiayue Melissa Shi2, Violeta J Rodriguez3

  • 1Luddy School of Informatics, Computing, and Engineering, Indiana University Indianapolis, 535 W Michigan St, Indianapolis, IN, 46202, United States, 1 317 278 4123.

JMIR Mental Health
|April 2, 2026
PubMed
Summary

People with lived experience of depression seek accurate information, emotional validation, and privacy in large language model (LLM) mental health chatbots. Design should prioritize safety and complement human support for depression self-management.

Keywords:
AILLMartificial intelligencechatbotcoping skillsdepressionharmslarge language modelmental healthself-management

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Area of Science:

  • Artificial Intelligence in Mental Health
  • Human-Computer Interaction
  • Digital Mental Health Interventions

Background:

  • Large language models (LLMs) are increasingly used for mental health support, including depression self-management.
  • Rapid deployment risks include inaccurate information, lack of empathy, and inadequate crisis support, especially when user priorities are overlooked.

Purpose of the Study:

  • To explore the experiences of individuals with lived experience of depression using an LLM-based chatbot for self-management.
  • To identify perceived benefits, limitations, and concerns to inform harm-mitigating design.

Main Methods:

  • A GPT-4o-based chatbot (Zenny) simulated depression self-management scenarios.
  • 17 individuals with lived experience of depression were interviewed after interacting with the chatbot.
  • Qualitative content analysis was applied to interview transcripts, notes, and chat logs.

Main Results:

  • Participants prioritized informational accuracy and applicability, expressing concerns about incorrect or vague information.
  • Emotional support was valued, but participants recognized limits in machine empathy and desired human connection.
  • A personalization-privacy dilemma emerged, with users wanting tailored guidance but withholding sensitive data.

Conclusions:

  • Individuals with lived experience of depression seek actionable information, emotional validation with defined limits, and privacy-preserving personalization from LLM chatbots.
  • Design strategies should mitigate harms, positioning LLM tools as complements to human support in depression recovery.