[Research progress on the role of non-coding RNAs in the pathogenesis of pulmonary fibrosis]

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive fibrotic lung disease. It is the most common form of irreversible interstitial pneumonia. The etiology of IPF is not fully understood, its detection, diagnosis and treatment options are limited, and its morbidity and mortality are high. Therefore, elucidating the molecular pathological mechanism of the occurrence and progression of IPF can provide theoretical basis for finding new targets for diagnosis and treatment of IPF. Non-coding RNAs have been confirmed to be involved in a variety of physiological and pathological processes and play important roles in the occurrence and progression of many different diseases, including lung diseases. In this review, the role of the non-coding RNAs in the occurrence and progression of IPF and the exploration of them as clinical diagnostic markers of IPF are reviewed, with a view to provide new ideas for the diagnosis and treatment of IPF at the molecular level.