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Engineering the efficient Exo-Cas12i2 for MITE manipulation in rice
Nan Chai1, Wuge Liu2, Kangli Sun2
1College of Agriculture, South China Agricultural University, Guangzhou, 510642, China.
Journal of Integrative Plant Biology
|April 2, 2026
Abstract
None:
Exo-Cas12i2 v1, a fusion of the 5' exonucleases T5E and PapE, facilitates editing of TA-rich regions and mediates deletions of large genomic fragments. Exo-Cas12i2 v1-driven MITE manipulation enables precise regulation of genes involved in gibberellin-mediated cell elongation and root ethylene responses to generate favorable agronomic traits.

