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Manufacture and Drug Delivery Applications of Silk Nanoparticles
Published on: October 8, 2016
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Advances in Polymeric Drug Delivery Systems: From Biodegradability to Nanocarrier Technologies
Abhay Thakur1, Rohit Sharma2, Shriyanshu Thakur3
1School of Pharmaceutical and Health Sciences, Career Point University, Hamirpur, (H.P)-176041, India.
Protein and Peptide Letters
|April 3, 2026
Summary
Biodegradable polymers are key for advanced drug delivery, improving treatment by controlling drug release and reducing side effects. These materials offer eco-friendly and biocompatible solutions for targeted therapies.
Area of Science:
- Polymer Science
- Materials Science
- Pharmaceutical Sciences
Background:
- Biodegradable polymers are essential in modern drug delivery systems.
- They offer controlled drug release and reduced toxicity.
- Their eco-friendly and biocompatible nature enhances therapeutic efficacy.
Purpose of the Study:
- To review different types of biodegradable polymers for drug delivery.
- To explore their production methods and release mechanisms.
- To evaluate their impact on controlled-release drug delivery technologies.
Main Methods:
- Categorization of polymers into natural, synthetic, and biodegradable types.
- Analysis of polymer development and design strategies.
- Assessment of drug release mechanisms (diffusion, degradation, swelling).
- Evaluation of polymeric nanocarriers (micelles, nanoparticles, dendrimers, hydrogels).
Main Results:
- Biodegradable polymers effectively manage drug release and minimize toxic reactions.
- Polymeric nanocarriers enhance drug targeting, prolong release, and improve solubility of hydrophobic drugs.
- These polymers show promise in treating conditions like cancer and ocular disorders.
Conclusions:
- Biodegradable polymers are pivotal in advancing controlled-release drug delivery.
- Their unique properties offer significant improvements in therapeutic outcomes.
- Further research and application in various therapies are warranted.
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