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Updated: Apr 4, 2026

Development of a Neonatal Rat Model for Brachial Plexus Birth Injury
Published on: March 27, 2026
The Association of Hospital Characteristics with Brachial Plexus Birth Injury
Mary Claire Manske1, Barton Wise2, Yueju Li2
1CHILDREN'S HOSPITAL OF PHILADELPHIA.
Insights
Hospital characteristics like lower obstetric care levels and higher proportions of Black births are linked to increased brachial plexus birth injury (BPBI) risk. These associations remained consistent across racial groups.
Area of Science:
- Obstetrics and Gynecology
- Pediatric Surgery
- Health Services Research
Background:
- Brachial plexus birth injury (BPBI) is a significant concern in obstetrics.
- Understanding factors contributing to BPBI is crucial for prevention and improved outcomes.
- Racial disparities in healthcare necessitate examining associations within diverse patient populations.
Purpose of the Study:
- To evaluate the association between hospital characteristics and the incidence of brachial plexus birth injury (BPBI).
- To determine if these associations differ based on the race of the infant.
- To identify specific hospital-level factors that may increase BPBI risk.
Main Methods:
- Retrospective analysis of liveborn infants from 1997-2019 using the Kids' Inpatient Database.
- Data linkage with the American Hospital Association Annual Survey for hospital characteristics.
- Multivariable logistic regression models and interaction terms to assess adjusted associations and effect modification by race.
Main Results:
- Analysis included 7,824,862 sampled infants, representing over 25 million births.
- Lower obstetric care level, hospital complications, and hospitals in the highest quartile of Black births were associated with increased BPBI risk.
- Associations between hospital characteristics and BPBI were consistent across all racial groups.
Conclusions:
- Hospital characteristics related to resources, quality, and patient demographics are associated with BPBI.
- Higher proportions of Black infants in a hospital were linked to greater BPBI odds, even after adjusting for individual factors.
- This suggests potential unmeasured structural differences in obstetric care delivery impacting BPBI risk.
Objective:
Evaluate association between hospital characteristics and brachial plexus birth injury (BPBI) and whether associations vary by race.
Study Design:
Retrospective study of liveborn infants from 1997-2019 using the Kids' Inpatient Database linked to American Hospital Association Annual Survey. Multivariable logistic regression models were used to assess adjusted associations between hospital characteristics and BPBI. Interaction terms were examined to evaluate effect modification by race.
Results:
7,824,862 sampled infants, representing 25,400,023 infants in the population, were included. After adjustment, lower obstetric care level, complications, or hospitals within highest quartile of Black births were associated with BPBI. Associations between hospital characteristics and BPBI were consistent across racial groups.
Conclusion:
Hospital characteristics reflecting institutional resources, quality, and patient population are associated with BPBI. BPBI odds were greatest in hospitals with greater proportion of Black infants even after adjustment for individual sociodemographics and risk factors, suggesting additional, unmeasured structural differences in obstetric care delivery.
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