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Updated: Apr 4, 2026
A Protein Microarray Assay for Serological Determination of Antigen-specific Antibody Responses Following Clostridium difficile Infection
Published on: June 15, 2018
Relationship Between Clostridioides difficile Stool Concentration, Nucleic Acid Amplification Test Results, and
Mary Morgan Lee1, Kimberly A Reske1, Tiffany Hink1
1Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.
None:
We compared rectal swab nucleic acid amplification testing (NAAT) with stool culture to detect Clostridioides difficile colonization and correlated results with environmental contamination. Rectal swab NAAT sensitivity (43%) for detecting toxigenic C. difficile colonization was low. Toxigenic culture-positive patients were more likely to have C. difficile detected in the hospital environment.
