Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response01:15

Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response

478
Circadian rhythms are cyclic changes that are crucial in plasma drug concentrations. Various standard circadian parameters, including core body temperature, heart rate, and other cardiovascular factors, directly impact disease states and the therapeutic response to drug therapy.
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
478
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

547
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
547

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prognostic Value of mRNAsi/Corrected mRNAsi Calculated by the One-Class Logistic Regression Machine-Learning Algorithm in Glioblastoma Within Multiple Datasets.

Frontiers in molecular biosciences·2021
Same author

Cellular and Molecular Mechanism of Traditional Chinese Medicine on Ventricular Remodeling.

Frontiers in cardiovascular medicine·2021
Same author

Detailed mapping of behavior reveals the formation of prelimbic neural ensembles across operant learning.

Neuron·2021
Same author

Association Between 2D- and 3D-Speckle-Tracking Longitudinal Strain and Cardiovascular Magnetic Resonance Evidence of Diffuse Myocardial Fibrosis in Heart Transplant Recipients.

Frontiers in cardiovascular medicine·2021
Same author

FootAssure: A multimodal, in-home wound detection device for diabetic peripheral neuropathy.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2021
Same author

Guanxin V protects against ventricular remodeling after acute myocardial infarction through the interaction of TGF-β1 and Vimentin.

Phytomedicine : international journal of phytotherapy and phytopharmacology·2021

Related Experiment Video

Updated: Apr 4, 2026

Collecting Sleep, Circadian, Fatigue, and Performance Data in Complex Operational Environments
08:36

Collecting Sleep, Circadian, Fatigue, and Performance Data in Complex Operational Environments

Published on: August 8, 2019

13.0K

Inflammatory marker dynamics in shift work sleep disorder: a data-driven approach among rotating shift workers.

Yiren Bao1, Bo Liang2, Tianhao Zhan3

  • 1Department of Massage, The Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.

Frontiers in Neuroscience
|April 3, 2026
PubMed
Summary
This summary is machine-generated.

Shift work sleep disorder (SWSD) is linked to significant changes in blood cell counts and inflammatory markers over time. These findings highlight potential risks associated with circadian disruption in shift workers.

Keywords:
circadian rhythmcross-sectional studiesinflammationshift work schedulesleep disorders

More Related Videos

Human Circadian Phenotyping and Diurnal Performance Testing in the Real World
10:16

Human Circadian Phenotyping and Diurnal Performance Testing in the Real World

Published on: April 7, 2020

9.2K
Through-the-Wall Blood Sampling Method to Minimize Sleep Disruption in Clinical Settings
06:39

Through-the-Wall Blood Sampling Method to Minimize Sleep Disruption in Clinical Settings

Published on: June 13, 2025

600

Related Experiment Videos

Last Updated: Apr 4, 2026

Collecting Sleep, Circadian, Fatigue, and Performance Data in Complex Operational Environments
08:36

Collecting Sleep, Circadian, Fatigue, and Performance Data in Complex Operational Environments

Published on: August 8, 2019

13.0K
Human Circadian Phenotyping and Diurnal Performance Testing in the Real World
10:16

Human Circadian Phenotyping and Diurnal Performance Testing in the Real World

Published on: April 7, 2020

9.2K
Through-the-Wall Blood Sampling Method to Minimize Sleep Disruption in Clinical Settings
06:39

Through-the-Wall Blood Sampling Method to Minimize Sleep Disruption in Clinical Settings

Published on: June 13, 2025

600

Area of Science:

  • Hematology
  • Sleep Medicine
  • Chronobiology

Background:

  • Shift work sleep disorder (SWSD) adversely impacts health and quality of life.
  • Understanding the long-term effects of SWSD on hematological parameters is crucial.

Purpose of the Study:

  • To investigate the association between SWSD and blood cell counts (BCCs).
  • To analyze the longitudinal trends of inflammatory indices in relation to SWSD over three years.

Main Methods:

  • Retrospective cross-sectional study design.
  • Involved rotating shift workers stratified by sex and sleep status.
  • Linear mixed-effects models were used to analyze longitudinal data.

Main Results:

  • SWSD was associated with increased neutrophil levels in both sexes over time.
  • Several composite inflammatory indices showed significant upward trends in individuals with SWSD.
  • A sex-specific increase in platelet-to-lymphocyte ratio was observed in males with SWSD.

Conclusions:

  • Long-term rotating shift work with sleep disorders leads to dynamic alterations in BCCs and inflammatory markers.
  • These changes suggest a link between circadian disruption and hematological alterations in shift workers.
  • Findings may inform future risk stratification and monitoring strategies for affected populations.