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Updated: Jun 6, 2026

The Soft Agar Colony Formation Assay
Published on: October 27, 2014
Molecular epidemiology and clinical differentiation between Clostridioides difficile infection and colonization
Andrew M Skinner1,2, Do Young Kim3, Adam Cheknis4
1Department of Medicine and Division of Infectious Diseases, University of Utah, Salt Lake City, UT, USA.
Abstract:
In a retrospective cohort study at three Chicago academic medical centers, 22/81 (27.2%) patients with a clinically adjudicated positive C. difficile test result were colonized. Recent antibiotic usage predicted true infection (adjusted odds ratio: 4.38 for infection). Restriction endonuclease analysis(REA) group Y (29.3%) replaced BI (9.3%) as the dominant strain.
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