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Related Experiment Video

Updated: Apr 4, 2026

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter
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Ocular higher order aberrations: A comparison between myopes and emmetropes.

Indu Govind1, C L Antony2, Sajeev Cherian Jacob2

  • 1East Point College of Medical Sciences and Research Centre, Bengaluru, Karnataka, India.

Oman Journal of Ophthalmology
|April 3, 2026
PubMed
Summary

Myopic eyes exhibit higher levels of higher-order aberrations (HOAs) compared to emmetropic eyes. This comparative study analyzed wavefront data to understand these visual distortions.

Keywords:
Emmetropiamyopiaocular higher order aberrationsspherical aberrationvertical coma

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Area of Science:

  • Ophthalmology
  • Optometry
  • Vision Science

Background:

  • Higher-order aberrations (HOAs) significantly impact visual quality.
  • Understanding HOAs in different refractive groups is crucial for vision correction strategies.

Purpose of the Study:

  • To compare higher-order aberrations (HOAs) between myopic and emmetropic individuals.
  • To investigate the relationship between refractive error and HOA levels.

Main Methods:

  • Cross-sectional comparative study involving 288 myopic and 322 emmetropic eyes.
  • Wavefront analysis using a Baush and Lomb Zywave aberrometer with a 6 mm pupil diameter.
  • Analysis of Zernike coefficients up to the fifth order.

Main Results:

  • Myopic eyes showed a statistically significant negative correlation between spherical equivalent and total HO RMS.
  • Emmetropic eyes exhibited a positive correlation between age and total HO RMS.
  • Significant differences in vertical coma and fourth-order spherical aberration were found between groups, with myopes having higher total HO RMS (0.444 ± 0.167 μm vs 0.412 ± 0.156 μm).

Conclusions:

  • Myopic eyes present with greater total higher-order aberrations than emmetropic eyes.
  • These findings highlight refractive error as a factor influencing HOA profiles.