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Targeted Cancer Therapies02:57

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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Updated: Apr 4, 2026

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy
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Chemo-Nonresponsive Telangiectatic Osteosarcoma With Oligometastatic Recurrence Managed With Multimodality Therapy

Wayne S Orr1, Srinivasan Vijayakumar2,3,4, Youssef Al Hmada5

  • 1SOM-Surgery-Transplant, University of Mississippi Medical Center, Jackson, USA.

Cureus
|April 3, 2026
PubMed
Summary

This case study shows prolonged survival in an osteosarcoma patient with advanced disease. Multimodality care, including stereotactic ablative body radiotherapy (SABR), achieved a significant treatment effect.

Area of Science:

  • Oncology
  • Radiotherapy
  • Surgical Oncology

Background:

  • Osteosarcoma is an aggressive bone cancer with poor outcomes for high-risk patients.
  • Limited response to chemotherapy and early metastasis are poor prognostic factors.
Keywords:
chemoresistant tumor cellsinnovation in medicinemetastatic osteosarcomaosteosarcoma researchprecision cancer medicineprecision immuno-oncologyprecision medicine oncologyradiation and clinical oncologyradiobiotherapystereotactic ablative body radiotherapy

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