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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
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Optimized Minimally Invasive Transscleral Subretinal Injection Technique in Mouse
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Refractory Unilateral Diffuse Scleritis With Negative Autoimmune Workup Successfully Treated With Sub-tenon

Narayana Swamy1, Saraswathi Saiprasad2, Kristi Kway3,4

  • 1Rheumatology, Baylor Scott and White Health, Fort Worth, USA.

Cureus
|April 3, 2026
PubMed
Summary

Steroid-dependent anterior scleritis can be challenging to manage. Localized intrascleral triamcinolone successfully resolved a patient's chronic scleritis, allowing discontinuation of systemic steroids.

Area of Science:

  • Ophthalmology
  • Rheumatology
  • Immunology

Background:

  • Noninfectious anterior scleritis presents management challenges due to potential steroid dependence.
Keywords:
idiopathic scleritisintrascleral triamcinolonerefractory ocular inflammationscleritisunilateral scleritis

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  • Recurrent cases may require extensive systemic evaluation to exclude other causes.
  • Systemic therapies can be ineffective for refractory scleritis.