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The average temperature of Earth is the subject of much current discussion. Earth is in radiative contact with both the Sun and dark space; it receives almost all its energy from the radiation of the Sun and reflects some of it into outer space. Dark space is very cold, about 3 K, so Earth radiates energy into it. For instance, heat transfer occurs from soil and grasses, the rate of which can be so rapid that frost can occur on clear summer evenings, even in warm latitudes.
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Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
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Reinforcement learning for real-time adaptive radiotherapy.

Kenneth Lau1, Jana Tumova2, David Broman2

  • 1EECS and Digital Futures, KTH Royal Institute of Technology, Stockholm, 100 44, Sweden; Elekta Instrument AB, Hagaesplanaden 4, Stockholm, 113 68, Sweden.

Artificial Intelligence in Medicine
|April 3, 2026
PubMed
Summary
This summary is machine-generated.

This study introduces a novel reinforcement learning (RL) approach for real-time adaptive radiotherapy. It enables precise radiation delivery by adapting to patient motion, minimizing dose discrepancies.

Keywords:
Adaptive radiotherapyMLC trackingReinforcement learning

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Area of Science:

  • Medical Physics
  • Oncology
  • Artificial Intelligence

Background:

  • Magnetic Resonance-Linear Accelerators (MR-Linacs) enable real-time tumor tracking for precise radiotherapy.
  • Current adaptive radiotherapy relies on geometric tracking, not the delivered radiation dose.
  • Real-time dose-based adaptation is complex due to high dimensionality.

Purpose of the Study:

  • To develop a radiotherapy simulator and a reinforcement learning (RL) approach for real-time adaptive radiotherapy.
  • To utilize 2D fluence as a surrogate for 3D dose in adaptive radiotherapy.
  • To enable adaptive radiotherapy that closes the feedback loop by considering delivered dose.

Main Methods:

  • Development of a radiotherapy simulator.
  • Proposal of a novel reinforcement learning (RL)-based algorithm for adaptive radiotherapy.
  • Utilizing 2D fluence as a proxy for real-time dose monitoring and adaptation.

Main Results:

  • Demonstrated feasibility of RL for closing the feedback loop in adaptive radiotherapy.
  • Successful dynamic adaptation to patient motion during simulated treatment.
  • Minimized discrepancies between delivered and intended radiation dose in clinical scenarios.

Conclusions:

  • Reinforcement learning offers a viable solution for real-time adaptive radiotherapy.
  • The proposed method allows for dynamic treatment adjustments based on motion and reference fluence.
  • This approach represents a new paradigm in radiotherapy delivery, moving beyond predefined machine settings.