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Updated: Apr 5, 2026
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Induction of Endothelial Differentiation in Cardiac Progenitor Cells Under Low Serum Conditions
Published on: January 7, 2019
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Rebuilding the bridge: Functional AVN cells for cardiac repair
1Department of Pathology and Laboratory Medicine, McAllister Heart Institute, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Cell Stem Cell
|April 3, 2026
Abstract:
Directing the differentiation of human pluripotent stem cells into atrioventricular node-like cells is a critical strategy for restoring atrioventricular node dysfunction in patients. In this issue, Lohbihler et al. define a BMP2-driven protocol to engineer functional conduction bridges that recapitulate the heart's native "gatekeeper" properties in vivo.
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