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Updated: Jun 28, 2026

Exploring the Potential of Mesenchymal Stem Cell Sheet on The Development of Hepatocellular Carcinoma In Vivo
Published on: September 11, 2018
A snapshot of the earliest stages of hepatocellular carcinoma
Álvaro Andrades1, Jan O Korbel2
1Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
Abstract:
How premalignant tissue transforms into cancer remains an open question. In this issue of Cancer Cell, Zhang et al. address this by comparing early hepatocellular carcinomas with matched premalignant tissue, revealing potential paths for malignant transformation: one characterized by high copy-number alteration burden and one characterized by high inflammation.
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