Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

357
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
357
Relative Risk01:12

Relative Risk

2.6K
Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...
2.6K
Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

341
In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
341
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

554
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
554
Drug Toxicity: Risk factors01:24

Drug Toxicity: Risk factors

182
Adverse Drug Reactions (ADRs) are potential complications that arise during pharmacotherapy, influenced by multiple risk factors. Age plays a significant role; both neonates and the elderly are at heightened risk due to their respective immature and diminished metabolic and elimination processes. Gender also impacts ADRs, with females experiencing a 1.5 to 1.7-fold greater risk than males, which may be linked to pharmacokinetic, pharmacodynamic, and hormonal differences. Notably, neonates, the...
182

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pre-existing injuries and illnesses in trail running: sex-based epidemiological findings from a 2022 forest marathon.

The Physician and sportsmedicine·2026
Same author

Navigating Adversity: Non-Completion and Evacuation of Trail Runners at the 2022 Magoebaskloof Forest Marathon.

South African journal of sports medicine·2026
Same author

Improving social support among sports medicine practitioners: a call to action.

British journal of sports medicine·2026
Same author

Mental health symptoms among men and women Australian professional football (soccer) players: a survey-based cross-sectional study.

BMC sports science, medicine & rehabilitation·2026
Same author

The 2026 Men's FIFA Football World Cup: Evidence-Based Guidelines to Protect Player Health and Performance from Environmental Challenges.

Sports medicine (Auckland, N.Z.)·2026
Same author

One Step Further: Integrating Evidence-Based Guidelines into Practice to Address Environmental Challenges at the Men's 2026 FIFA World Cup.

Sports medicine (Auckland, N.Z.)·2026

Related Experiment Video

Updated: Apr 5, 2026

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack
07:31

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack

Published on: May 15, 2020

8.3K

Content Validation of a Medication Adherence Risk Score (MARS) for Mortality Risk Prediction: A Delphi Consensus.

Jessica Hamuy Blanco1, Dina C Janse van Rensburg2, Audrey Jansen van Rensburg2

  • 1Department of Pharmacology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.

Clinical Pharmacology and Therapeutics
|April 3, 2026
PubMed
Summary

The Medication Adherence Risk Score (MARS) can predict mortality risk. Expert consensus validates its use for risk stratification and reducing healthcare costs.

More Related Videos

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
06:55

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index

Published on: January 8, 2020

15.5K

Related Experiment Videos

Last Updated: Apr 5, 2026

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack
07:31

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack

Published on: May 15, 2020

8.3K
Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
06:55

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index

Published on: January 8, 2020

15.5K

Area of Science:

  • Health Economics
  • Public Health
  • Biostatistics

Background:

  • The Medication Adherence Risk Score (MARS) is an objective measure derived from dispensary data.
  • Validating MARS as a mortality risk predictor is crucial for healthcare management.

Purpose of the Study:

  • To achieve expert consensus on the validity and implementation of the MARS for predicting mortality risk.
  • To assess the MARS's relevance, predictive power, and feasibility in South African healthcare.

Main Methods:

  • A systematic review of South African health legislation and guidelines.
  • A two-round modified Delphi approach with 13 experts using a 5-point Likert scale.
  • Consensus defined as ≥80% agreement; nonconsensus statements were revised and reevaluated.

Main Results:

  • Initial consensus was reached on 20 of 28 statements in Round 1.
  • Areas needing revision included risk score components, validity/predictive power, and implementation.
  • All 28 statements achieved consensus after revision and a second round of evaluation.

Conclusions:

  • Expert consensus supports the MARS's components, predictive value for mortality, and feasible real-world application.
  • The MARS can enhance risk stratification and potentially reduce healthcare costs.
  • Further statistical analysis and implementation strategies are needed for clinical integration.