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Artificial Intelligence Tools for Gastrointestinal Research: A Practical Guide.

Christina S Gainey1, Hersh Shroff1, Oren K Fix1

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Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association
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Summary
This summary is machine-generated.

Artificial intelligence (AI) tools can aid manuscript writing for gastroenterology (GI) researchers. Responsible use with human verification is key to accelerating the process and ensuring accuracy.

Keywords:
Artificial IntelligenceGastroenterologyLarge Language ModelsManuscript WritingScientific Publishing

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Area of Science:

  • Biomedical Research
  • Artificial Intelligence in Science
  • Gastroenterology

Background:

  • Growing adoption of AI tools, including large language models (LLMs), in biomedical research.
  • Limited practical guidance for integrating AI into manuscript writing workflows.
  • Need for structured approaches for GI researchers and clinicians.

Purpose of the Study:

  • Provide a step-by-step guide for responsible AI use in GI manuscript preparation.
  • Evaluate AI tools for literature searching, data analysis, figure generation, and drafting.
  • Offer a risk-stratified framework for AI integration.

Main Methods:

  • Literature review, expert recommendations, and author evaluation of AI tools.
  • Selection based on relevance to GI manuscript workflow, availability, and maintenance.
  • Assessment across four domains: literature search, data analysis, figure generation, manuscript drafting/editing.
  • GI-specific examples and head-to-head comparisons.
  • Risk assessment for fabrication, bias, and misuse.

Main Results:

  • AI tools effectively synthesize literature/data, generate statistical code for visualizations, draft tables/figures, and refine academic writing.
  • Tool maturity varies; general LLMs show high reference fabrication rates.
  • AI-generated images may lack necessary precision.
  • Independent verification of all AI outputs is crucial.

Conclusions:

  • AI tools can accelerate GI manuscript writing with proper safeguards.
  • A risk-stratified framework is proposed, emphasizing essential human verification.
  • Transparent disclosure of AI use is recommended for all submissions.