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American Gastroenterological Association-North American Society for Pediatric Gastroenterology, Hepatology and

Leonel Rodriguez1, Lusine Ambartsumyan2, Kayla Baumgartner3

  • 1Section of Pediatric Gastroenterology and Hepatology, Department of Pediatrics, Yale School of Medicine, New Haven, Connecticut.

Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association
|April 5, 2026
PubMed
Summary

This new clinical care pathway offers a standardized approach for diagnosing and managing functional constipation (FC) in children, improving care for pediatric patients. It guides clinicians through evaluation, treatment, and transition to adult care.

Keywords:
Clinical PathwayFunctional ConstipationPediatric GastroenterologyRome IV CriteriaTransition of Care

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Area of Science:

  • Pediatric Gastroenterology
  • Clinical Care Pathways

Background:

  • Functional constipation (FC) is a common pediatric condition affecting quality of life and healthcare use.
  • Existing diagnostic and management approaches for pediatric FC can be inconsistent.

Purpose of the Study:

  • To develop a collaborative clinical care pathway for pediatric functional constipation.
  • To provide a structured, practical approach for diagnosing and managing FC in children.

Main Methods:

  • A multi-disciplinary expert panel convened to discuss the current state of pediatric FC.
  • A consensus-driven approach was used to formulate standardized recommendations.
  • The pathway integrates Rome IV criteria with a symptom-based diagnostic strategy.

Main Results:

  • The pathway emphasizes history and physical examination for diagnosis, limiting the need for extensive testing.
  • It outlines tiered treatment strategies, including lifestyle changes, medications, and subspecialty referrals.
  • Guidance is provided for special populations and transitioning care to adult services.

Conclusions:

  • The AGA-NASPGHAN pathway standardizes pediatric FC evaluation and management.
  • This practical approach aims to improve clinical decision-making and patient outcomes.
  • Future research should explore implementation and long-term effectiveness.