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Related Experiment Video

Updated: Apr 6, 2026

Fabrication of a Master Mold for Microneedles with a Micron-sized Air-vent Hole

Fabrication of a Master Mold for Microneedles with a Micron-sized Air-vent Hole

Published on: December 5, 2025

Microneedle: classification, preparation and applications.

Jichuan Kong¹, Miao Shi¹, Feng Zhou¹

¹School of Medicine, Henan Polytechnic University, 454000 Jiaozuo, PR China.

International Journal of Pharmaceutics

|April 5, 2026

Summary

Microneedles offer a minimally invasive way to deliver drugs and diagnostics through the skin. This review details their design, production methods, and applications, aiding future research and industrial use.

Keywords:

Application Classification Clinical translation Microneedle Preparation

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Last Updated: Apr 6, 2026

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Area of Science:

Biomedical Engineering
Materials Science
Pharmacology

Background:

Microneedles are a novel technology for transdermal delivery of therapeutics and diagnostics.
They offer a minimally invasive alternative to traditional drug delivery methods.

Purpose of the Study:

To comprehensively review microneedle technology, including structural design, materials, and manufacturing techniques.
To compare preparation methods, analyze their advantages and disadvantages, and assess translational feasibility.
To explore microneedle applications in disease treatment, diagnosis, and medical aesthetics, and address clinical translation challenges.

Main Methods:

Systematic review and comparative analysis of microneedle preparation techniques.
Evaluation of structural design, material composition, and technological development.
Analysis of clinical application scenarios and translational bottlenecks.

Main Results:

Detailed comparison of various microneedle fabrication methods, highlighting their benefits, drawbacks, and scalability.
Identification of optimal application contexts for different microneedle types.
Overview of advancements in microneedle use for medical aesthetics and disease management.

Conclusions:

Microneedle technology presents significant advantages over traditional therapies for drug delivery and diagnostics.
Understanding preparation techniques is crucial for industrial production and clinical translation.
Addressing regulatory and translational challenges is key for future development and widespread adoption.