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Updated: Apr 7, 2026

Brain Imaging Investigation of the Neural Correlates of Emotional Autobiographical Recollection
Published on: August 26, 2011
Autobiographical memory specificity to attachment-related cues improves in major depression during initial
Jonathan Raphael Nowak1,2, Ede Nagy1,2, Maximilian Orth1,2
1Department of General Internal Medicine, Psychosomatics, and Psychotherapy, University of Heidelberg, Heidelberg, Germany.
Objective:
Patients with depression tend to retrieve fewer specific autobiographical memories, a phenomenon linked to insecure attachment and emotion regulation. This study examined changes in autobiographical memory (AM) specificity in response to attachment-related cues during the initial phase of psychodynamic psychotherapy, as early change is predictive of later outcome and central psychodynamic processes occur at this stage.
Method:
Seventy-four outpatients with major depression were assessed twice during early psychodynamic psychotherapy (baseline and after M = 10.5 sessions, range = 7-21). A modified Autobiographical Memory Test with attachment-related cues was used alongside measures of depression (BDI-II), anxiety (STAI), perseverative thinking (PTQ), attachment (ECR), and emotion regulation (EAQ). Robust regression analysis examined variables associated with change in attachment-cued AM (AC-AM).
Results:
Patients recalled more specific AC-AMs after early treatment. Depression, anxiety, and perseverative thinking decreased. Higher baseline attachment anxiety was associated with less improvement in AC-AM specificity, whereas higher baseline attachment avoidance and greater reductions in affective suppression were associated with greater improvement.
Conclusion:
During early psychodynamic treatment, patients with depression showed increased AC-AM specificity. Early gains appeared moderated by attachment style and affective suppression, suggesting that memory specificity improvement reflects emerging psychodynamic change processes related to attachment and affect regulation.
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