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Patch Testing in Individuals With Diabetes Using Medical Devices. Part 2-Contact Allergy to Medical Device Allergens
Josefin Ulriksdotter1, Martin Mowitz1, Thanisorn Sukakul1
1Department of Occupational and Environmental Dermatology, Lund University, Skåne University Hospital, Malmö, Sweden.
Contact Dermatitis
|April 5, 2026
Summary
Contact allergy to diabetes medical devices (MDs) is common, especially in users with skin issues. New data highlights the need for updated patch testing to prevent allergic reactions to these essential devices.
Area of Science:
- Dermatology
- Allergology
- Materials Science
Background:
- Previous research on contact allergy to diabetes medical devices (MDs) relied on patients already experiencing suspected allergic contact dermatitis.
- This study addresses the gap by investigating real-world prevalence in a broader user population.
Purpose of the Study:
- To determine the prevalence of contact allergy to allergens within diabetes MDs among users.
- To propose an optimized patch test series for identifying these allergies.
Main Methods:
- 204 adults with type 1 diabetes using MDs were patch tested.
- Participants included those with and without skin rashes related to their devices.
- A novel MD patch test series was utilized.
Main Results:
- 16.2% of all participants showed positive reactions to MD allergens.
- The prevalence was significantly higher in those with skin rashes (28.1%) compared to those without (1.1%).
- Key allergens identified included isobornyl acrylate (10.3%) and N,N-dimethylacrylamide (4.9%).
Conclusions:
- Contact allergy to diabetes MD allergens is highly prevalent in users.
- 2-hydroxyethyl acrylate, newly identified as a culprit allergen, necessitates ongoing chemical analysis and updated testing series.
- Improved prevention strategies for MD-related contact allergies are crucial.
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