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Evaluation of antimicrobial prophylaxis procedures in cardiac surgery patients with delayed sternal closure
Ahmed Albakheet1, Brian Schuler1, Felicia Wang1
1Pharmacy, https://ror.org/04b6nzv94Brigham and Women's Hospital, Boston, USA.
Abstract:
Implementation of a 24-hour antimicrobial prophylaxis guideline for patients with delayed sternal closure significantly reduced broad-spectrum post-operative antimicrobial use without increasing surgical site infection risk in 75-patient cohort. The median duration of prophylaxis decreased from 120 to 45 hours, and surgical site infection rates were 3% pre-intervention versus 0% post-intervention.
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