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Related Concept Videos

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Coronary Artery Disease I: Introduction

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Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
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Related Experiment Video

Updated: Apr 7, 2026

Visualization of Intensity Levels to Reduce the Gap Between Self-Reported and Directly Measured Physical Activity
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Visualization of Intensity Levels to Reduce the Gap Between Self-Reported and Directly Measured Physical Activity

Published on: March 7, 2019

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The Association Between Sedentary Behavior and Cardiovascular Disease Risk: An Analysis Based on NHANES Data.

Heming Huang1, Zhe Zhao2,3, Zemou Yu4

  • 1Geriatric Department, Shenzhen People's Hospital, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen, Guangdong, China, jnu.edu.cn.

Cardiovascular Therapeutics
|April 6, 2026
PubMed
Summary

Reducing sedentary time is crucial for cardiovascular health. Prolonged sedentary behavior significantly increases cardiovascular disease (CVD) risk, especially in older adults.

Keywords:
CVDNHANEScardiovascular diseaserisk factorssedentary behavior

Related Experiment Videos

Last Updated: Apr 7, 2026

Visualization of Intensity Levels to Reduce the Gap Between Self-Reported and Directly Measured Physical Activity
05:59

Visualization of Intensity Levels to Reduce the Gap Between Self-Reported and Directly Measured Physical Activity

Published on: March 7, 2019

7.4K

Area of Science:

  • Public Health
  • Cardiovascular Medicine
  • Epidemiology

Background:

  • Sedentary behavior is a global public health issue linked to cardiovascular disease (CVD).
  • It acts as an independent risk factor for CVD, but mechanisms require further exploration.
  • Understanding these links is vital for targeted public health interventions.

Purpose of the Study:

  • To investigate the association between sedentary behavior and cardiovascular disease (CVD) risk.
  • To identify key demographic and clinical factors influencing this relationship.
  • To establish thresholds for sedentary time that elevate CVD risk.

Main Methods:

  • Analysis of 31,034 participants from the National Health and Nutrition Examination Survey (NHANES).
  • Utilized questionnaires for sociodemographic and health data collection.
  • Employed logistic regression and restricted cubic spline regression for statistical analysis.

Main Results:

  • Significant association found between prolonged sedentary time and increased CVD risk (OR = 17.297, p < 0.001) in those aged 60+.
  • Age, gender, and hyperlipidemia were critical influencing factors.
  • CVD risk increased markedly after 250 minutes and sharply after 750 minutes of sedentary time.

Conclusions:

  • Sedentary behavior is a significant independent risk factor for CVD.
  • Reducing sedentary time is linked to lower CVD risk.
  • Public awareness and interventions, particularly for the elderly, are recommended to improve cardiovascular health.