Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hybrid Zones02:29

Hybrid Zones

22.5K
Hybrid zones are narrow regions where two closely related species interact, mate, and produce hybrids. Relative to either parent species, hybrids may possess distinct phenotypic or genetic differences that impact their survival and reproductive success. The genetic variances introduced by hybridization influence species diversity and speciation processes within the hybrid zone.
22.5K
Genetics of Speciation02:16

Genetics of Speciation

23.3K
Speciation is the evolutionary process resulting in the formation of new, distinct species—groups of reproductively isolated populations.
23.3K
Formation of Species01:31

Formation of Species

46.9K
Speciation describes the formation of one or more new species from one or sometimes multiple original species. The resulting species are discrete from the parent species, and barriers to reproduction will typically exist. There are two primary mechanisms, speciation with and without geographic isolation—allopatric and sympatric speciation, respectively.
46.9K
What is a Species?01:17

What is a Species?

52.1K
Overview
52.1K
Speciation Rates01:07

Speciation Rates

23.5K
Overview
23.5K
Synteny and Evolution02:31

Synteny and Evolution

4.0K
John H. Renwick first coined the term “synteny” in 1971, which refers to the genes present on the same chromosomes, even if they are not genetically linked. The species with common ancestry tend to show conserved syntenic regions. Therefore, the concept of synteny is nowadays used to describe the evolutionary relationship between species.
Around 80 million years ago, the human and mice lineages diverged from the common ancestor. During the course of evolution, the ancestral...
4.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Divergence Linked to Possible Ecological Speciation in Blind Mole Rats: Integration of Thermal Biology and Bite Force in the Upper Galilee Blind Mole Rat (Nannospalax galili).

Integrative zoology·2026
Same author

Genome evolution and regulatory dynamics underlying salt stress tolerance in the halophyte Halogeton arachnoideus.

Communications biology·2026
Same author

Heteromorphic XY chromosomes with pericentromeric recombination suppression in Hippophae (Elaeagnaceae).

The New phytologist·2026
Same author

Genomic insights into chromosomal fusion and its evolutionary implications for zokors.

Molecular biology and evolution·2026
Same author

Climate and species traits give rise to complex phenological dynamics.

Ecology·2026
Same author

Hybrid origin and phenotype evolution of the modern maize.

Journal of integrative plant biology·2025
Same journal

Refugia, but Not for Everyone: Genetic Structure Differentiates Shallow and Mesophotic Populations of the Brooder Sponge Ircinia variabilis.

Molecular ecology·2026
Same journal

Leafcutter Ant Farmers Prevent Loss of Edible Symbiotic Structures by Maintaining Allelic Diversity in Their Multinucleate Fungal Crop.

Molecular ecology·2026
Same journal

Resolving Emergent Patterns in Community Genetics With Environmental DNA.

Molecular ecology·2026
Same journal

Genomic Offsets Predict Survival With Low Accuracy in a Marine Common Garden.

Molecular ecology·2026
Same journal

Differential Immune Responses Correlate With Chytridiomycosis Severity in Italian Crested Newts.

Molecular ecology·2026
Same journal

Demography and Environment Shapes Genetic Variation: Spatiotemporal Genetic Dynamics in Cyclic Voles at Low Latitudes.

Molecular ecology·2026
See all related articles

Related Experiment Video

Updated: Apr 7, 2026

Manipulation of Gene Function in Mexican Cavefish
07:01

Manipulation of Gene Function in Mexican Cavefish

Published on: April 22, 2019

10.2K

Chromosomal Fusions Promote Speciation in Subterranean Blind Mole Rats.

Zhuoran Kuang1,2, Xiaojie Yang1, Zachariah Gompert3

  • 1State Key Laboratory of Grassland Agro-Ecosystems, College of Ecology, Lanzhou University, Lanzhou, China.

Molecular Ecology
|April 6, 2026
PubMed
Summary
This summary is machine-generated.

Chromosomal fusions drive speciation in blind mole rats by altering genome structure and reducing gene flow. These rearrangements, facilitated by repetitive elements, offer insights into evolutionary divergence.

Keywords:
3D‐architecturechromosomal fusiongene flowspeciation

More Related Videos

Author Spotlight: Optimizing Supraclavicular Brown Adipose Tissue Extraction for Genetic Analysis
06:50

Author Spotlight: Optimizing Supraclavicular Brown Adipose Tissue Extraction for Genetic Analysis

Published on: March 29, 2024

3.5K
Genome Editing in Astyanax mexicanus Using Transcription Activator-like Effector Nucleases TALENs
07:42

Genome Editing in Astyanax mexicanus Using Transcription Activator-like Effector Nucleases TALENs

Published on: June 20, 2016

8.9K

Related Experiment Videos

Last Updated: Apr 7, 2026

Manipulation of Gene Function in Mexican Cavefish
07:01

Manipulation of Gene Function in Mexican Cavefish

Published on: April 22, 2019

10.2K
Author Spotlight: Optimizing Supraclavicular Brown Adipose Tissue Extraction for Genetic Analysis
06:50

Author Spotlight: Optimizing Supraclavicular Brown Adipose Tissue Extraction for Genetic Analysis

Published on: March 29, 2024

3.5K
Genome Editing in Astyanax mexicanus Using Transcription Activator-like Effector Nucleases TALENs
07:42

Genome Editing in Astyanax mexicanus Using Transcription Activator-like Effector Nucleases TALENs

Published on: June 20, 2016

8.9K

Area of Science:

  • Genomics
  • Evolutionary Biology
  • Molecular Biology

Background:

  • Understanding large-scale chromosomal rearrangements and their evolutionary impact is crucial.
  • Blind mole rats exhibit varying chromosome numbers, making them ideal for studying chromosomal evolution.

Purpose of the Study:

  • To investigate the genomic mechanisms and evolutionary consequences of chromosomal fusions in blind mole rats.
  • To elucidate the role of chromosomal rearrangements in speciation and genome architecture.

Main Methods:

  • Generated chromosome-level genomes for two sister species pairs of blind mole rats.
  • Analyzed chromosomal fusions, repetitive elements, and three-dimensional genome architecture.
  • Investigated gene flow and signatures of selection near fusion points.

Main Results:

  • Identified five chromosome fusions during the divergence of blind mole rat species.
  • Discovered that three shared fusions led to the Spalax galili-S. golani clade divergence.
  • Found independent fusions in S. galili and S. carmeli, associated with altered genome architecture and reduced gene flow.
  • Observed that chromosomal fusions correlated with selection signatures and may involve centromeric repeat expansion.

Conclusions:

  • Chromosomal fusions are key drivers of lineage divergence and speciation in blind mole rats.
  • Repetitive elements and centromeric repeat expansion facilitate chromosomal fusions.
  • Fusion events impact genome organization, gene flow, and evolutionary trajectories.