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Related Experiment Video

Updated: Apr 7, 2026

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Update on Therapy for Non-Infectious Scleritis.

Allison Richey1, Victoria Sattarova2, Laura J Kopplin3

  • 1Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, MN, USA.

Clinical Ophthalmology (Auckland, N.Z.)
|April 6, 2026
PubMed
Summary
This summary is machine-generated.

Non-infectious scleritis, a serious inflammatory eye condition, demands long-term management. This review covers current and emerging treatments, including medications and biologics, to control inflammation and preserve vision.

Keywords:
glucocorticoidsimmunosuppressive agentsnon-steroidal anti-inflammatory agentstherapeutics

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Area of Science:

  • Ophthalmology
  • Rheumatology
  • Immunology

Background:

  • Non-infectious scleritis is a severe, vision-threatening inflammatory eye disease.
  • Effective management often necessitates prolonged therapeutic interventions.

Purpose of the Study:

  • To review established and novel therapeutic strategies for managing non-infectious scleritis.
  • To provide an overview of treatment options for ophthalmologists and rheumatologists.

Main Methods:

  • Literature review of current and emerging therapies for scleritis.
  • Categorization of treatments including topical agents, systemic medications, and biologics.

Main Results:

  • Scleritis treatment involves systemic evaluation and targeted anti-inflammatory agents.
  • Therapeutic options range from NSAIDs and corticosteroids to immunomodulatory drugs and biologics.

Conclusions:

  • A comprehensive approach combining systemic workup and appropriate pharmacotherapy is crucial for scleritis.
  • Emerging biologic therapies offer new avenues for managing this complex inflammatory condition.