Update on Therapy for Non-Infectious Scleritis

Area of Science:

• Ophthalmology
• Rheumatology
• Immunology

Background:

• Non-infectious scleritis is a severe, vision-threatening inflammatory eye disease.
• Effective management often necessitates prolonged therapeutic interventions.

Purpose of the Study:

• To review established and novel therapeutic strategies for managing non-infectious scleritis.
• To provide an overview of treatment options for ophthalmologists and rheumatologists.

Main Methods:

• Literature review of current and emerging therapies for scleritis.
• Categorization of treatments including topical agents, systemic medications, and biologics.

Main Results:

• Scleritis treatment involves systemic evaluation and targeted anti-inflammatory agents.
• Therapeutic options range from NSAIDs and corticosteroids to immunomodulatory drugs and biologics.

Conclusions:

• A comprehensive approach combining systemic workup and appropriate pharmacotherapy is crucial for scleritis.
• Emerging biologic therapies offer new avenues for managing this complex inflammatory condition.