Related Experiment Video
Updated: Apr 7, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
A Real-World Study on Medical Resource Consumption in Multidrug-Resistant Organism Infections Under the DRG Payment
Dongping Jiang1, Yuan Liu1, Sen Yang2
1Hospital Infection Management Department, Suining Central Hospital, Suining, Sichuan, 629000, People's Republic of China.
Multidrug-resistant organism (MDRO) infections significantly increase hospital length of stay and costs in China. Targeted control of high-incidence MDRO Diagnosis-Related Groups (DRG) is crucial for effective hospital cost management.
Area of Science:
- Healthcare Economics
- Infectious Diseases
- Hospital Management
Background:
- Diagnosis-Related Groups (DRG) is the primary payment model in China.
- Multidrug-resistant organism (MDRO) infections are rising, impacting patient outcomes and resource utilization.
- Understanding the economic burden of MDROs is vital for healthcare systems.
Purpose of the Study:
- To quantify the impact of MDRO infections on medical resource consumption in a Chinese tertiary hospital.
- To provide data for precise prevention and cost management strategies under the DRG system.
- To analyze resource consumption differences between MDRO-infected and non-infected patients.
Main Methods:
- Retrospective analysis of discharge data from January 2023 to December 2024.
- Comparison of resource consumption (LOS, costs) between MDRO-infected and non-infected patient groups.
- Stratification analysis of resource consumption by Diagnosis-Related Groups (DRG).
Main Results:
- MDRO infections led to significantly higher Time Consumption Index (TCI) and Cost Consumption Index (CCI) (P < 0.05).
- Carbapenem-resistant Gram-negative bacilli (CR-GNB) showed higher resource consumption than Methicillin-resistant Staphylococcus aureus (MRSA).
- In high-infection-rate DRGs, MDRO-infected patients had longer LOS and higher costs, with increased non-medical discharge and mortality.
Conclusions:
- MDRO infections substantially increase medical resource consumption and costs.
- Targeted control of high-incidence MDROs within specific DRGs is essential.
- Hospitals need to adapt strategies to manage MDROs effectively within the DRG payment model.
More Related Videos
Related Concept Videos
Mechanism of Antibiotic Resistance in MRSA
Drug Accumulation During Multiple Dosing: Intermittent IV Infusions
Clinical Significance of Antibiotic Resistance
Impact of Pharmacokinetic–Pharmacodynamic Models: Regulatory Decisions
Treatment Resistant Cancers
Pulmonary Tuberculosis V
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...

