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Multidisciplinary Management in the Diabetes Reversal Clinic Promotes Diabetes Remission
Zihan Zhang1, Ruilin Shen1, Doudou Li2
1Department of Endocrinology, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China.
AACE Endocrinology and Diabetes
|April 6, 2026
Summary
A multidisciplinary approach in a Diabetes Reversal Clinic led to significant type 2 diabetes remission (29.24%) and improved metabolic health. This comprehensive management strategy offers a promising alternative to conventional care for diabetes reversal.
Area of Science:
- Endocrinology
- Metabolic Diseases
- Public Health
Background:
- Type 2 diabetes management often relies on conventional outpatient care.
- The need for effective strategies to achieve diabetes remission and improve metabolic outcomes is critical.
Purpose of the Study:
- To investigate the remission rate and metabolic outcomes in patients with type 2 diabetes undergoing multidisciplinary management at a Diabetes Reversal Clinic.
- To compare the effectiveness of this model against standard care.
Main Methods:
- Enrolled patients with type 2 diabetes from April 2022 to December 2024.
- Implemented comprehensive multidisciplinary management: personalized plans, lifestyle modification, continuous glucose monitoring, and traditional Chinese medicine.
- Analyzed remission rates, target glycated hemoglobin A1c levels, and changes in metabolic indicators after 6 months.
Main Results:
- 50 out of 171 patients (29.24%) achieved diabetes remission after 6 months.
- 149 patients (87.13%) reached a glycated hemoglobin A1c target of < 53 mmol/mol (7.0%).
- Significant improvements were observed in BMI, waist circumference, fasting blood glucose, HbA1c, HOMA-IR, and HDL cholesterol (P < 0.05).
Conclusions:
- The multidisciplinary management model in the Diabetes Reversal Clinic achieved a 29.24% diabetes remission rate and an 87.13% target HbA1c rate within 6 months.
- This approach demonstrates superiority over conventional management for promoting diabetes remission and metabolic reversal.
- Highlights the potential of integrated care for type 2 diabetes management.
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