Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cancer Vaccines01:30

Cancer Vaccines

1.3K
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
1.3K
Vaccinations01:51

Vaccinations

54.1K
Overview
54.1K
Vaccines01:21

Vaccines

51
Vaccines are among the most effective tools in preventive medicine, designed to prepare the immune system to recognize and combat infectious agents. By introducing antigens—substances that the immune system identifies as foreign—vaccines stimulate an adaptive immune response that leads to immunological memory. This immunological memory enables the body to mount a faster and more effective response upon future exposures to the actual pathogen.Vaccines can be categorized based on the...
51

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dual-modular-nanobody CAR-T cell technical platform against the solid tumor microenvironment.

Journal of hematology & oncology·2026
Same author

TCR-mimic bispecific nanobody-based T cell engager targeting intracellular tumor antigens for cancer immunotherapy.

Signal transduction and targeted therapy·2026
Same author

<i>UBA1-CDK16</i>: A female-specific chimeric RNA emerging through evolution and involved in immune regulation.

Science advances·2026
Same author

Association between body roundness index and all-cause and cardiovascular disease mortality in maintenance hemodialysis patients: evidence from a prospective cohort study in Southern China.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association·2026
Same author

Integrated Metabolomic, Proteomic, and Transcriptomic Analyses Reveal the Mechanism Underlying Brightness Differences in Eggplant (<i>Solanum melongena</i>) Peels.

Journal of agricultural and food chemistry·2025
Same author

Zanubrutinib plus salvage chemotherapy in patients with refractory/relapsed diffuse large B-cell lymphoma non-candidate for autologous stem cell transplantation: A retrospective study.

Annals of hematology·2025

Related Experiment Video

Updated: Apr 7, 2026

Preparation of Tumor Antigen-loaded Mature Dendritic Cells for Immunotherapy
08:40

Preparation of Tumor Antigen-loaded Mature Dendritic Cells for Immunotherapy

Published on: August 1, 2013

18.8K

Dendritic cell vaccines: Current research progress, challenges, and opportunities.

Shilin Zhang1,2, Shanzhao Mo3,2, Wenxing Huang1,2

  • 1College & Hospital of Stomatology, Guangxi Medical University, Nanning, Guangxi 530021, China.

Genes & Diseases
|April 6, 2026
PubMed
Summary

Dendritic cell (DC) vaccines represent a promising cancer immunotherapy. Advanced preparation techniques and combination therapies are being explored to enhance their anti-tumor efficacy and overcome current challenges.

Keywords:
Cancer vaccineCombination therapyDendriticcell vaccinesImmunosuppressionImmunotherapy

More Related Videos

Chemical Conjugation of a Purified DEC-205-Directed Antibody with Full-Length Protein for Targeting Mouse Dendritic Cells In Vitro and In Vivo
10:35

Chemical Conjugation of a Purified DEC-205-Directed Antibody with Full-Length Protein for Targeting Mouse Dendritic Cells In Vitro and In Vivo

Published on: February 5, 2021

4.1K
Generation of a Novel Dendritic-cell Vaccine Using Melanoma and Squamous Cancer Stem Cells
12:43

Generation of a Novel Dendritic-cell Vaccine Using Melanoma and Squamous Cancer Stem Cells

Published on: January 6, 2014

12.3K

Related Experiment Videos

Last Updated: Apr 7, 2026

Preparation of Tumor Antigen-loaded Mature Dendritic Cells for Immunotherapy
08:40

Preparation of Tumor Antigen-loaded Mature Dendritic Cells for Immunotherapy

Published on: August 1, 2013

18.8K
Chemical Conjugation of a Purified DEC-205-Directed Antibody with Full-Length Protein for Targeting Mouse Dendritic Cells In Vitro and In Vivo
10:35

Chemical Conjugation of a Purified DEC-205-Directed Antibody with Full-Length Protein for Targeting Mouse Dendritic Cells In Vitro and In Vivo

Published on: February 5, 2021

4.1K
Generation of a Novel Dendritic-cell Vaccine Using Melanoma and Squamous Cancer Stem Cells
12:43

Generation of a Novel Dendritic-cell Vaccine Using Melanoma and Squamous Cancer Stem Cells

Published on: January 6, 2014

12.3K

Area of Science:

  • Immunology
  • Oncology
  • Biotechnology

Background:

  • Dendritic cells (DCs) are crucial antigen-presenting cells linking innate and adaptive immunity.
  • DCs activate cytotoxic T lymphocytes and natural killer cells, essential for anti-tumor responses.
  • DC-based vaccines aim to enhance T-cell-mediated tumor destruction.

Purpose of the Study:

  • To review advancements in dendritic cell (DC)-based cancer immunotherapies.
  • To explore various DC vaccine preparation techniques, including genetic modification and cell fusion.
  • To examine the integration of DC vaccines with other immunotherapies.

Main Methods:

  • Review of literature on dendritic cell vaccine development.
  • Analysis of techniques such as peptide pulsing, genetic modification, and cell fusion (e.g., using polyethylene glycol).
  • Examination of preclinical and clinical data on fusion cell vaccines and alternative vector approaches.

Main Results:

  • DC vaccines, including fusion cell vaccines, show anti-tumor efficacy in preclinical and clinical studies.
  • Advanced techniques like genetic modification and cell fusion improve DC vaccine potential.
  • Integration with other immunotherapies is being investigated to address tumor-induced immunosuppression.

Conclusions:

  • Dendritic cell vaccines play a vital role in cancer therapy.
  • Ongoing research focuses on refining therapeutic strategies and clinical validation.
  • Combination therapies and advanced preparation methods are key to augmenting DC vaccine efficacy.