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Intramuscular Ganglion Cyst of the Extensor Digitorum Longus.

Ramy Saade1, Ahmad Hammad1, Jean Paul Rizk1

  • 1Department of Orthopedics Surgery, American University of Beirut Medical Center, Beirut, Beirut Governate, Lebanon, aubmc.org.lb.

Case Reports in Orthopedics
|April 6, 2026
PubMed
Summary

This case report details a rare intramuscular ganglion cyst in the knee, a synovial cyst typically found in the wrist and hand. Diagnosis and treatment involved surgical excision and histopathological assessment.

Keywords:
ganglion cystintramuscular ganglion cystsoft tissue tumorsurgical excision

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Area of Science:

  • Orthopedic Surgery
  • Musculoskeletal Radiology
  • Pathology

Background:

  • Ganglion cysts are common synovial cysts, typically presenting in the wrist and hand.
  • Intramuscular locations, particularly in the lower extremity, are rare and underreported.
  • This study focuses on an unusual case of an intramuscular ganglion cyst in the knee.

Purpose of the Study:

  • To report a rare case of an intramuscular ganglion cyst in the knee.
  • To highlight the importance of considering rare diagnoses in atypical locations.
  • To emphasize diagnostic and therapeutic strategies for intramuscular cysts.

Main Methods:

  • A 34-year-old female presented with a symptomatic knee mass.
  • Radiography revealed an intramuscular multiseptated cystic lesion.
  • Open excisional biopsy with histopathological assessment was performed.

Main Results:

  • Radiography showed an intramuscular cystic lesion within the extensor digitorum longus muscle.
  • No intra-articular extension or capsular communication was observed.
  • Histopathological assessment confirmed the lesion as a ganglion cyst.

Conclusions:

  • Intramuscular ganglion cysts are rare and require thorough differential diagnosis.
  • Surgical excision with histological confirmation is crucial for diagnosis and treatment.
  • This approach helps rule out malignancy and prevent recurrence.