Spontaneous Pneumothorax Revealing Pulmonary Alveolar Microlithiasis: A Case Report
Jamal Oujaber1, Amine Harzimi Benjelloun1, Soufiane Sassi1
1Pulmonology Department, Avicenne Military Hospital, Marrakech, MAR.
Cureus
|April 6, 2026
Summary
Pulmonary alveolar microlithiasis, a rare lung disease, can present with spontaneous pneumothorax. Histological confirmation is crucial for diagnosing this condition characterized by calcium phosphate buildup.
Area of Science:
- Pulmonology
- Rare Diseases
- Radiology
Background:
- Pulmonary alveolar microlithiasis is a rare autosomal recessive lung disease.
- Characterized by intra-alveolar accumulation of calcium phosphate microliths.
- Diagnosis is often incidental on chest imaging, with histology as the gold standard.
Related Concept Videos
Pneumothorax-I
A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
Pneumothorax-II
Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
Clinical Manifestations:
Pneumothorax II: Pathophysiology
Pneumothorax means the presence of air in the pleural space — the thin potential gap between the visceral and parietal pleura. This condition disrupts the normal pressure balance that keeps the lungs inflated, leading to partial or complete collapse of the affected lung.Normal physiologyUnder normal conditions, the pleural space maintains a slightly negative intrapleural pressure, which keeps the lungs expanded against the chest wall. This negative pressure creates a delicate balance between...
Atelectasis II: Pathophysiology
Atelectasis develops when alveoli lose their air and collapse inward. Because lung tissue is naturally elastic, these air sacs shrink rather than remaining open. Collapsed alveoli are no longer ventilated, reducing their role in gas exchange. Blood flow may continue in these regions, creating a ventilation–perfusion mismatch. Clinical findings include decreased breath sounds, dullness to percussion, reduced chest expansion, and decreased tactile fremitus as sound transmission through collapsed...


